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Mechanical Cardiac Support 2000: Current Applications and Future Trail Design
... the majority of cases, initial testing does not establish efficacy, and clinical equipoise can be maintained for the ...
http://www.acc.org/Clinical/consensus/mechanical/t

bmj.com Abstracts: Donovan et al. 325 (7367): 766
Home Help Search/Archive Feedback Table of Contents Full text of this article PDF of this article Email this article to a friend Respond to this article Read responses to this article Related ... ... Design: Controversial ProtecT (prostate testing for cancer and treatment) trial embedded ... that recruiters had difficulty discussing equipoise and presenting treatments equally; they ...
http://www.bmj.com/cgi/content/abstract/325/7367/7

bmj.com Donovan et al. 325 (7367): 766
Home Help Search/Archive Feedback Table of Contents PDF of this article Email this article to a friend Respond to this article Read responses to this article Related letters in BMJ See related ... ... Design: Controversial ProtecT (prostate testing for cancer and treatment) trial embedded ... that recruiters had difficulty discussing equipoise and presenting treatments equally; they ...
http://www.bmj.com/cgi/content/full/325/7367/766

Stats: Ethics of a placebo group
Dear Professor Mean, Some of my colleagues want to use placebos in their research, but I have warned them about the ethical issues surrounding the use of a placebo group. When (if ever) is it ... ... sugar pill or other inert substance, when testing a medication. ... also involve some sham procedure, when testing a medical procedure. ... than they can by testing it against a serious ...
http://www.cmh.edu/stats/plan/placebo.asp

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Class #51: The ethics of placebo controlled trials
This class will teach you some of the ethical problems associated with the use of a placebo group in a medical research study. This class is useful for anyone who is planning a research study that ... ... inert substance, when testing a medication. It can also involve some sham procedure, when testing a medical procedure. ...
http://www.cmh.edu/stats/training/hand51.asp

Circulation -- Stevenson et al. 103 (2): 337
... A systematic approach to testing pharmacologic therapies in heart failure has arisen only within the last 20 years. ...
http://circ.ahajournals.org/cgi/content/full/103/2

Pre-Visit Education to Promote Shared Decision-Making for Prostate Cancer Screening
The overall effect is to facilitate shared decision-making without any additional physician-initiated intervention. ... in PSA testing with an educational intervention These studies have several limitations (equipoise, outcome, difficult to ...
http://www.napcrg.org/2002handouts/ps148.ppt


Chapter 4: Human and Animal Experimentation Introduction Ethical issues raised by biomedical experimentation (or research) using human subjects. ... due to a misunderstanding of the concept of equipoise (balance) - that is ethically required in RCTs. ... radioactive fallout from open air testing of atomic bombs in the 1950's ...
http://www.okstate.edu/artsci/philosophy/rhodes/ch

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